Introduction Humanized mice are exceptional models for preclinical testing of cell and gene therapies. Standard mouse models can provide an approximation of human systems, but the murine immune system has important differences from humans. To overcome these...
Introduction A patient-derived colon cancer Xenograft (PDX) model has been established for the first time by Noble Life Sciences by implanting cryopreserved PDX fragments into a transplant compliant mouse host. PDX models have advantages over cancer cell line...
Introduction With the increasing incidence of patients worldwide diagnosed with cancer, the development of effective, safe, and economically viable anticancer therapeutics remains a high priority. Early anticancer drug discovery and development is very challenging...