If you’ve worked in drug development, whether it be at a biotech or pharma company, you know just how critical Good Laboratory Practice (GLP) toxicology studies are in the preclinical process. These studies help evaluate the safety and potential risks associated with...
As biotechnology, pharmaceutical, and medical device development companies venture into the crucial phase of Investigational New Drug (IND) enabling studies, they face a multitude of challenges. These preclinical studies are fundamental to evaluating the safety and...
Preclinical studies are essential for advancing oncology drug development programs. They provide valuable insights into a drug candidate's safety and efficacy before it moves into clinical trials. A well-designed preclinical study can increase the likelihood of...
Sykesville, Maryland - June 20, 2023 Noble Life Sciences, a leading contract research organization in Maryland, is proud to announce that it has received renewed accreditation from the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC)...
Introduction Humanized mice are exceptional models for preclinical testing of cell and gene therapies. Standard mouse models can provide an approximation of human systems, but the murine immune system has important differences from humans. To overcome these...
Introduction A patient-derived colon cancer Xenograft (PDX) model has been established for the first time by Noble Life Sciences by implanting cryopreserved PDX fragments into a transplant compliant mouse host. PDX models have advantages over cancer cell line...
Introduction With the increasing incidence of patients worldwide diagnosed with cancer, the development of effective, safe, and economically viable anticancer therapeutics remains a high priority. Early anticancer drug discovery and development is very challenging...