Introduction The study aims to establish an orthotopic liver cancer model in nude mice and evaluate the anti-tumor efficacy of Sorafenib. Liver cancer is a leading cause of cancer deaths worldwide, accounting for approximately 830,000 deaths each year. Hepatocellular...
Noble Life Sciences, in collaboration with ImQuest Biosciences, has optimized the peritonitis/sepsis mouse model to screen for new antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA). The model’s popularity derives from its ease of use with small and expensive animals, short-duration experiments with reproducible infections, and simple end-points.
The mouse and ferret animal models are the most widely used models for influenza studies. Each has its advantages. The mouse model provides a relatively low-cost system with a variety of genetic backgrounds and an arsenal of commercially available immunologic reagents...
The in vivo animal tumor models possessing fully functional immunity are essential for preclinical research of new immunotherapeutic medicine. Syngeneic tumor models are powerful in vivo animal models that meet the need in preclinical research for testing innovative...
Figure 1. Overview of the biodistribution study of cell/gene therapy (CGT) product. The CGT product is injected into mice; tissue samples are harvested and DNA is isolated from all samples. DNA is then quantified and used as a template in quantitative polymerase chain...