GLP Custom Polyclonal Antibodies

For over 30 years, Noble Life Sciences has supplied custom polyclonal antibody services using a variety of animal species. Our GLP custom polyclonal antibodies are ideal for vaccine potency testing. We offer two standard protocols which are designed to maximize antibody production in terms of levels of antibody, avidity and volume of serum. Client-specific protocols may also be used for immunization.

SERVICE OPTIONS

  • GLP or non-GLP
  • Immunogen preparation
  • Antibody purification
  • Titer analysis
  • Biodistribution

SPECIES OPTIONS

  • Goats
  • Sheep
  • Donkeys
  • Llamas
  • Mice and rats
  • Others on request
  • Rabbits
  • Guinea Pigs
  • Donkeys
  • Ferrets

ADDITIONAL SERVICES

Immunoassay Development Services
Noble will design, optimize, and validate your immunoassay. Immunoassays can be performed using ELISA, ELIspot, and flow cytometry

Vaccine Development Services
Noble has experience with a variety of mammalian species used for vaccine discovery and development. We have performed studies ranging from a 3-ferret influenza challenge to 250-guinea pig immunogenicity study.

  • Immunogenicity testing
  • Immunization protocol development
  • Multiple routes of administration

PROTOCOLS

Standard Protocol

GLP Custom Polyclonal Antibodies
73 days
4 immunizations
3 blood collections

Fast Protocol

53 days
3 immunizations
3 blood collections

SPECIES OPTIONS

  • Plasmapheresis for large animals
  • Protocol extensions
  • Custom protocols available

Adjuvants

  • Initial injection with Freund’s Complete Adjuvant; subsequent injections with Freund’s Incomplete Adjuvant
  • Other adjuvants also available

Immunogens

  • Proteins, peptides, DNA, cells and lysates
  • Prepared from solution, precipitate, acrylamide gel band, nitrocellulose blot
  • Peptide sequence prediction, synthesis and conjugation

Antibody Purification

  • Affinity or protein A/G
  • Serum filtration

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Scientific Advisor Team

Our oncology team is committed to fight The Fight

by advancing your preclinical research.

Stephen K. Horrigan, Ph.D.

Stephen K. Horrigan, Ph.D.

Chief Scientific Officer

Pang-Kuo Lo, Ph.D. MSc

Pang-Kuo Lo, Ph.D. MSc

Team Lead, Assay Development

Arundhati Ghosh, Ph.D., MSc

Arundhati Ghosh, Ph.D., MSc

Study Director

Yongping Chen, M.D., Ph.D.

Yongping Chen, M.D., Ph.D.

Senior Study Director