Medical Device Testing Services

Noble Life Sciences offers a wide range of testing GLP services to ensure both the efficacy and safety of medical devices with significant expertise in orthopaedic, cardiovascular, trauma, and wound models. We provide surgical expertise and support utilizing state of the art equipment

SERVICE OPTIONS

  • GLP and non-GLP protocol development
  • Prototype evaluation
  • Multi-species in vivo testing
  • Novel preclinical model development
  • Complex surgical procedures
  • Regulatory support

OPERATIONS

  • FDA inspected GLP facility
  • Standard operating procedures (SOP’s) that cover all aspects of animal care, animal procedures, equipment operation and facility operation
  • Accredited by the Association for the Assessment and Accreditation of Laboratory Animal (AAALACi) since 1989
  • Operates in full accordance with the Animal Welfare Act and the PHS Policy on Humane Care and Use of Laboratory Animals and the NRC Guide for the Care and Use of Laboratory Animals

FACILITIES

  • 24,000 square feet of animal housing, support, and laboratory space securely situated in a one hundred acre campus
  • 8,000 sq. ft. of conventional and 14,000 sq. ft. of specific pathogen-free (SPF) housing and support space

STAFF

  • Surgeons, board-certified veterinarians, and AALAS-certified technicians with more than 15 years of medical device and GLP experience.
  • Research interventionalist to help with protocol development; catheter and device placement; and basic cardiology and electrophysiology
  • Quality assurance professionals over 25 years of experience

CAPABILITIES

Surgery

  • Two surgical suites with recovery room, intensive care area, and preparation area
  • Wide range of imaging, surgery and specialized equipment

Laboratory

  • Blood collection and processing
  • Necropsy, histology, pathology/ histopathology
  • Clinical pathology—clinical chemistry, hematology, coagulation factor and urinalysis

Imaging

  • Biophotonic imaging system for whole body, real-time in vivo imaging
  • C-arm imaging scanner intensifier with radiographic capabilities fo animal imaging
  • Radiography
  • Ultrasound

MODEL OPTIONS

Cardiovascular

  • Models of acute myocardial infarction (with or without reperfusion)
  • Heart valve studies
  • Peripheral arterial disease • Thrombosis models
  • Venous/arterial grafts
  • Cardiac assist devices
  • Microvascular surgery

Trauma

  • Critical care training for traumatic injuries
  • Hemostasis

Wound Healing

  • Full thickness defect
  • Skin graft
  • Burn models
  • Diabetic models

Orthopedics

  • Joint Models
  • Osteoarthritis
  • Arthroplasty (hip, knee) and other types of articular cartilage repair
  • Anterior cruciate ligament (ACL) repair/ meniscectomy
  • Artificial meniscus
  • Reconstruction/fixation of other ligaments and tendons
  • Artificial ligaments and tendons
  • Bone Defect Models
  • Osteotomy of femur, tibia and radius
  • Critical size defect models in the calvarium, tibia, fibula, femur,
    radius and ulna
  • Spinal Fusion Models
  • PLIF
  • PLIBF

SPECIES OPTIONS

  • Small animals: mice, rats, guinea pigs, hamsters, rabbits, and ferrets
  • Large animals: sheep, goats, domestic swine, mini pigs and other large animals

Interested in an Orthotopic Liver Cancer Model?

Scientific Advisor Team

Our oncology team is committed to fight The Fight

by advancing your preclinical research.

Stephen K. Horrigan, Ph.D.

Stephen K. Horrigan, Ph.D.

Chief Scientific Officer

Pang-Kuo Lo, Ph.D. MSc

Pang-Kuo Lo, Ph.D. MSc

Team Lead, Assay Development

Arundhati Ghosh, Ph.D., MSc

Arundhati Ghosh, Ph.D., MSc

Study Director

Yongping Chen, M.D., Ph.D.

Yongping Chen, M.D., Ph.D.

Senior Study Director