Preclinical Drug Development Services 2018-06-20T07:52:35+00:00

YOUR PRECLINICAL DEVELOPMENT PARTNER

PRECLINICAL DRUG DEVELOPMENT

Noble Life Sciences provides high-quality, GLP and non-GLP preclinical contract services that help you get from concept to clinic faster and more efficiently.  We have state-of-the-art facilities with laboratory and vivarium managed by an experienced staff.  With our stringent quality control and expertise in cell- & animal-based models, you can trust Noble scientists to help lead and support your drug development programs through each phase of the preclinical process.  With proof of concept studies, early safety assessments and other IND enabling services, we are committed to providing a strong scientific foundation to enable your preclinical decisions. We take pride in our ability to successfully customize studies to meet your needs. We will work with you to develop unique procedures and practices to facilitate the research and development of your product.

PROGRAM DEVELOPMENT AND IMPLEMENTATION

With extensive and successful experience in drug development, Noble’s scientists can manage your drug development program including design, implementation, and data management.  Noble can also develop plans for the management of therapeutic, clinical and business aspects of your drug development program.

We can help you devise a strategy and guide you through your preclinical testing or turn the entire project over to us and we will handle all aspects from protocol to final report.

Noble scientists will assist you with designing and implementing a variety of cell- and animal-based models for testing the efficacy of drugs and drug candidates. This includes human-mouse xenograft models developed using our extensive collection of cell lines from a broad variety of human cancers.

Examples of Studies

  • Pharmacokinetic and pharmacodynamic drug testing
  • Drug candidate formulation, development, and testing
  • Disease model optimization and testing
  • Exploratory toxicology
  • Non-GLP immunogenicity
  • Single dose acute including oral, dermal, irritation, and sensitization tests
  • Repeat dose toxicity
  • Biodistribution
  • Reproductive and developmental toxicity
  • Product release testing
  • Biomarker discovery and fit-for-purpose validation
  • Drug/biomarker pairing and validation studies
  • Custom assay development

Proven Expertise

We have experience with a variety of mammalian species used for vaccine and drug development. Our studies range from single digit to hundreds of animals.

Our scientists, with over 15 years of GLP experience, provide all aspects of the GLP process from design to regulatory support of your IND, IDE or PMA FDA submission.

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