Clinical Biomarker Development and Implementation 2018-06-20T07:41:49+00:00

THE SMART SOLUTION FOR

PRECLINICAL DEVELOPMENT

CLINICAL BIOMARKER DEVELOPMENT & IMPLEMENTATION

OUR SERVICES

Noble can develop strategies for the management of therapeutic, clinical and business aspects of your R&D program including:

  • Inclusive project and technology management for transitioning your candidate biomarker to a robust clinically viable test

  • Preclinical analysis of targets and biomarkers for identification of patient subpopulations that have enhanced potential for clinical activity

  • Identification and validation of patient stratification biomarkers in clinical samples

  • Evaluation of potential rationale combination therapies using cellular, animal, and clinical data analysis

  • Clinical study design and implementation of biomarker strategies

  • Evaluation and diligence for licensing and acquisition of technologies and business

 

PERSONALIZED MEDICINE

  • In today’s research climate, scientists are turning to biomarkers as tools to advance personalized medicine and  enhance the value of their drug development programs.

    “Personalized medicine is a disruptive innovation that will require the development of new business models…..To compete in this market, organizations will need new approaches, new relationships, and new ways of thinking.”

    From The New Science of Personalized Medicine: Translating Promise into Practice. PriceWaterhouseCoopers Report, 2010.

    The ability to match a patient population of a specific tumor type with drugs that are mechanistically-targeted to that tumor is a powerful approach to address the issues that drive the failure rate of drug candidates.

Proven Expertise

We have experience with a variety of mammalian species used for vaccine and drug development. Our studies range from single digit to hundreds of animals.

Our scientists, with over 15 years of GLP experience, provide all aspects of the GLP process from design to regulatory support of your IND, IDE or PMA FDA submission.

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